6645 Main Street, Buffalo, NY 14221

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Property Description

Main Street Williamsville Medical Office Space. 10,534 sq. ft. New long-term tenant in place occupying over 7,000 SF, with owner-user seeking leaseback. 6645 Main Street is situated in densely populated Williamsville, just west of Transit Rd. New HVAC (2023). 60+ car parks.

6645 Main Street | MLS# B1703907

This commercial property located at 6645 Main Street, Buffalo, NY 14221 is currently listed for sale with an asking price of $1,800,000. Main Street is located within the Williamsville school district. Search Buffalo real estate on www.coldwellbankerprime.com today.

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Property Features

Property Type: Commercial - Office

Basement: None

Cooling: Central Air

Heating: Other, See Remarks, Forced Air

Lot Size: 1.55 Acres

Roof Type: Shingle

Stories: 1.0

Taxes: $35,395

Year Built: 1992

Feature Descriptions

Days on Site: 1

Exterior: Brick

Flooring: Carpet, Linoleum, Vinyl

Lot: Rectangular, Rectangular Lot

Lot Dimensions: 279X245

Parcel#: 142289-081-020-0002-002-120

Parking: On Site, Surfaced

Parking Notes: On Site, Surfaced

Sewer: Public Sewer

Utilities: Sewer Connected

Local Schools

School District: Williamsville

Demographics

Listed By / Shown By

Listing By

Agency Name: Hanna Commercial
Agency Contact: 716-856-7107

Shown By

Agency Title: Coldwell Banker Prime Properties
Agency Phone: 866-323-CBPP

6645 Main Street, Buffalo, NY 14221

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Disclaimer: All information deemed reliable but not guaranteed. All properties are subject to prior sale, change or withdrawal. Neither listing broker(s) or information provider(s) shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. Listing(s) information is provided for consumers personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information on this site was last updated 08/05/2026. The listing information on this page last changed on 08/05/2026. The data relating to real estate for sale on this website comes in part from the Internet Data Exchange program of Delta Media Group MLS (last updated Wed 08/05/2026 12:00:06 AM EST) or Global MLS (last updated Tue 08/04/2026 11:52:24 PM EST) or New York State Alliance MLS (last updated Tue 08/04/2026 11:59:04 PM EST) or Hudson Valley Catskill Region MLS (last updated Tue 08/04/2026 11:51:15 PM EST) or Berkshire MLS (last updated Tue 08/04/2026 8:13:09 PM EST) or OneKey MLS (last updated Tue 08/04/2026 11:53:21 PM EST). Real estate listings held by brokerage firms other than Coldwell Banker Prime Properties may be marked with the Internet Data Exchange logo and detailed information about those properties will include the name of the listing broker(s) when required by the MLS. All rights reserved.

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Coldwell Banker®. All rights reserved. The Coldwell Banker System is comprised of company owned offices which are owned by a subsidiary of Anywhere Advisors LLC and franchised offices. Coldwell Banker Real Estate LLC, fully supports the principles of the Fair Housing Act and the Equal Opportunity Act. Any services or products provided by independently owned and operated franchisees are not provided by, affiliated with, or related to Coldwell Banker Real Estate LLC nor any of its affiliated companies.

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6645 Main Street, Buffalo, NY 14221

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Property Description

6645 Main Street | MLS# B1703907

Gallery

Property Features

Feature Descriptions

Local Schools

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6645 Main Street, Buffalo, NY 14221

Demographics

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6645 Main Street, Buffalo, NY 14221

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